Peto’s Paradox is a captivating conundrum in the realm of evolutionary biology and cancer research, prompting scientists to ponder a perplexing question: Why don’t large-bodied or long-lived animals, like whales and elephants, with their multitude of cells and extended lifetimes, exhibit a proportionally higher incidence of cancer compared to smaller species?
Named after the epidemiologist Richard Peto (see source 2 at the bottom of this post), this paradox challenges conventional understanding, suggesting that creatures like whales or elephants, despite having many more cells that could potentially turn cancerous over longer lifespans, don’t necessarily suffer from cancer more frequently than humans do. Unraveling the mystery behind this phenomenon could offer profound insights into cancer resistance and inform future therapeutic strategies.
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